
| Species: | Rabbit |
| Applications: | FC IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human IL-21 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 59067 |
| Swiss Prot: | Q9HBE4 |
| Synonyms: | Za11, IL-21, CVID11, Interleukin-21, IL21 |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
| Reacitivity: | Human, Mouse, Rat |