Species: | Rabbit |
Applications: | WB FC IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human CD50 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 3385 |
Swiss Prot: | |
Synonyms: | intercellular adhesion molecules-3, ICAM-3, ICAM 3, CD50, CDW 50, CDW50, ICAM 3, ICAM R, ICAMR. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA1 protein. ICAM3 is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Upon stimulation by a physiological stimulus it becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
Reacitivity: | Human |