Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human FAST kinase |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 79675 |
Swiss Prot: | |
Synonyms: | Fas-activated serine/threonine kinase, Fas activated serine threonine kinase, Fas activated serine threonine kinase isoform 1, Fas activated serine threonine kinase isoform 4, FAST, FAST kinase, FLJ13079. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full length natures have not yet been determined. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |