YRP17613-01 [Polyclonal Antibody]
Mettl14 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   KLH conjugated synthetic peptide derived from mouse Mettl14
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   210529
Swiss Prot:   Q3UIK4
Synonyms:   mKIAA1627, G430022H21Rik, N6-adenosine-methyltransferase subunit METTL14, Methyltransferase-like protein 14, Mettl14, Kiaa1627
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop (By similarity). M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (PubMed:24394384).
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information