YRP01724-01 [Polyclonal Antibody]
HPV16 E6 + HPV18 E6 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF
Immunogen Range:   synthetic peptide from HPV16 E6 + HPV18 E6 conjugated to KLH
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1489088
Swiss Prot:   P06463
Synonyms:   Protein E6, E6
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Virus (HPV16/HPV18)
For research use only. Not intended for diagnostic or therapeutic use!
Additional information