Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human CK II Alpha |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1457 |
Swiss Prot: | |
Synonyms: | Casein kinase 2 alpha 1 polypeptide, Casein kinase II alpha 1 subunit, Casein kinase II alpha chain, Casein kinase II alpha subunit, Casein kinase II subunit alpha, CK II, CK2 alpha, CK2 catalytic subunit alpha, CK2A1, CKII, CSNK2A1, CSK21_HUMAN. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | CKII is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The gene for this protein is found on chromosome 20, but a related transcribed pseudogene is found on chromosome 11. Three transcript variants have been found, encoding two different isoforms. Protein kinase CKII is recognized as one of the key cellular signals for cell growth and proliferation; it also has an important role in apoptosis. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |