Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human Mannose-binding protein C |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4153 |
Swiss Prot: | P11226 |
Synonyms: | MBL, MBP, MBP1, MBPD, MBL2D, MBP-C, COLEC1, HSMBPC, Mannose-binding protein C, Collectin-1, Mannan-binding protein, Mannose-binding lectin, MBL2 |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |