Species: | Rabbit |
Applications: | WB FC IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human CD105 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 2022 |
Swiss Prot: | P17813 |
Synonyms: | END, HHT1, ORW1, Endoglin, CD15, ENG |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
Reacitivity: | Human, Mouse, Rat |