Species: | Rabbit |
Applications: | WB FC IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from mouse Transcription factor SOX-2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 20674 |
Swiss Prot: | P48432 |
Synonyms: | lcc, ysb, Sox-2, Transcription factor SOX-2, Sox2 |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
Reacitivity: | Human, Mouse, Rat |