YRP00516-01
[Polyclonal Antibody]
FADD Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
KLH conjugated synthetic peptide derived from mouse FADD |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
14082 |
Swiss Prot: |
Q61160 |
Synonyms: |
Mort1/FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1 |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:100-1:1000
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!