
| Species: | Rabbit | 
| Applications: | WB IHC IF | 
| Immunogen Range: | KLH conjugated synthetic peptide derived from human Integrin beta 2 | 
| Clonality: | Polyclonal Antibody | 
| Isotype: | IgG | 
| GENE ID: | 3689 | 
| Swiss Prot: | P05107 | 
| Synonyms: | LAD, CD18, MF17, MFI7, LCAMB, LFA-1, MAC-1, Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, ITGB2 | 
| Purification: | Purified by Protein A. | 
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Background: | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. | 
| Caculated MW: | / | 
| Observed MW: | Refer to Figures | 
| Applications: | 
                                WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200  | 
                        
| Reacitivity: | Human, Mouse, Rat |