YRP01488-01
[Polyclonal Antibody]
RBBP6/P2P-R Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC IF |
Immunogen Range: |
KLH conjugated synthetic peptide derived from human P2PR |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
5930 |
Swiss Prot: |
Q7Z6E9 |
Synonyms: |
PACT, MY038, P2P-R, RBQ-1, SNAMA, E3 ubiquitin-protein ligase RBBP6, Proliferation potential-related protein, Protein P2P-R, Retinoblastoma-binding Q protein 1, Retinoblastoma-binding protein 6, p53-associated cellular protein of testis, RBBP6, P2PR, RBQ1 |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth. |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!