YRP01487-01 [Polyclonal Antibody]
CD177 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from rat CD177
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   499099
Swiss Prot:   D3ZCH9
Synonyms:   NB1 GP;PRV-1;HNA-2a;NB1 glycoprotein;Neutrophil Glycoprotein NB1, RGD1562941, CD177 antigen, Polycythemia rubra vera protein 1, PRV-1, NB1 glycoprotein, NB1 GP, Human neutrophil alloantigen 2a, HNA-2a, CD177, CD177_HUMAN, CD177_MOUSE.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97% of the caucasian population. against NB1 can be involved in neonatal alloimmune neutropenia (NAN).
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information