YRP13698-01 [Polyclonal Antibody]
NCKAP5 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human NCKAP5
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:  
Swiss Prot:  
Synonyms:   ERIH1, ERIH2, NAP-5, NAP5, Nck-associated protein 5, NCKAP5, NCKP5_HUMAN, Peripheral clock protein.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   NAP5 (Nck-associated protein 5), also known as peripheral clock protein, NCKAP5 or ERIH, is a 1,909 amino acid nuclear protein that is expressed in fetal and adult brain, leukocytes and fetal fibroblasts. Containing pro-rich sequences, NAP5 interacts with the adapter protein Nck via the SH3-containing region. Existing as four alternatively spliced isoforms, the gene encoding NAP5 maps to human chromosome 2q21.2 and mouse chromosome 1 E3. Human chromosome 2, the second largest human chromosome, consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene present on chromosome 2. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is due to mutations in the ALMS1 gene.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information