Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human HoxC13 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | |
Swiss Prot: | |
Synonyms: | ECTD9, Homeo box 3G, Homeo box C13, homeobox C13, Homeobox protein Hox 3G, Homeobox protein Hox-C13, Hox-3G, HOX3, HOX3G, HOXC13, HXC13, NUP98. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC13 (homeobox C13), also known as HOX3 or HOX3G, is a 330 amino acid protein that contains one homeobox DNA-binding domain and is a member of the Abd-B homeobox family. Localized to the nucleus, HoxC13 functions as a sequence-specific transcription factor that, in conjunction with a variety of other proteins, provides cells with positional identities on their anterior-posterior axis. Via its ability to modify features of the anterior-posterior body axis, HoxC13 is thought to play a role in the development of nails, hair and filiform papilla. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |