
| Species: | Rabbit | 
| Applications: | WB IHC IF | 
| Immunogen Range: | KLH conjugated synthetic peptide derived from human ChRM2 | 
| Clonality: | Polyclonal Antibody | 
| Isotype: | IgG | 
| GENE ID: | 1129 | 
| Swiss Prot: | P08172 | 
| Synonyms: | HM2, Muscarinic acetylcholine receptor M2, CHRM2 | 
| Purification: | Purified by Protein A. | 
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Background: | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol. | 
| Caculated MW: | / | 
| Observed MW: | Refer to Figures | 
| Applications: | 
                                WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200  | 
                        
| Reacitivity: | Human, Mouse, Rat, Dog | 
