Species: | Rabbit |
Applications: | FC IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human ZO-1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 7082 |
Swiss Prot: | Q07157 |
Synonyms: | ZO-1, Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1, TJP1, ZO1 |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
Reacitivity: | Human, Mouse, Rat, Pig |