Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human GSDML/Gasdermin like |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 55876 |
Swiss Prot: | |
Synonyms: | 123, 156, Gasdermin B, Gasdermin like protein, Gasdermin-B, Gasdermin-like protein, GSDMB, GSDMB_HUMAN, GSDML, PP4052, PRO2521. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | GSDML is a member of the GSDMDC (gasdermin-domain containing) family of proteins. Members of the GSDMDC family are involved in a wide variety of cellular processes, including cell-cycle control, extracellular matrix production, differentiation and apoptosis, and have been associated with the development and progression of cancer. GSDML is a widely expressed protein found in both cancerous and non-cancerous tissues localizing to the cytoplasm and in secretory vesicles. The gene encoding GSDML is thought to have been generated by a duplication event of the GSDM1 gene which encodes gasdermin. In addition, various isoforms exist for GSDML. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human |