Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human GANC/Neutral alphaglucosidase C |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 2595 |
Swiss Prot: | |
Synonyms: | Ganc, GANC_HUMAN, Glucosidase alpha neutral C, MGC138256, Neutral alpha glucosidase C, Neutral alpha-glucosidase C, Neutral alphaglucosidase C. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | A key enzyme in glycogen degradation and metabolism, GANC (glucosidase, ?¡À neutral C) is a 914 amino acid protein with ?¡À-glucosidase activity that belongs to the glycosyl hydrolase 31 family and hydrolyzes non-reducing, terminal 1,4-linked ?¡À-D-glucose residues and releases ?¡À-D-glucose. The gene encoding GANC maps to human chromosome 15q15.1, a region associated with susceptibility to non-insulin-dependent (type 2) diabetes mellitus, a disease characterized by high blood glucose levels. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized ge |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |