YRP13236-01 [Polyclonal Antibody]
FUT7/FucT-VII Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human FUT7/FucT-VII
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   2529
Swiss Prot:  
Synonyms:   3-fucosyltransferase, Alpha 1,3 fucosyltransferase, Alpha-1, Fuc-TVII, Fucosyltransferase 7, Fucosyltransferase VII, FucT VII, FucT-VII, FUT7, FUT7_HUMAN, Galactoside 3 L fucosyltransferase, Galactoside 3-L-fucosyltransferase, Selectin ligand synthase.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Alpha 1,3-fucosyltransferase VII (FucT-VII) mediates the targeting of effector T cells to sites of inflammation by modifying surface ligands which are compatible to endothelial selectins (7).
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information