YRP13113-01 [Polyclonal Antibody]
ESRP2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human ESRP2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   80004
Swiss Prot:  
Synonyms:   Epithelial splicing regulatory protein 2, ESRP 2, ESRP2, ESRP2_HUMAN, FLJ21918, FLJ22248, RBM35B, RNA binding mot protein 35A, RNA binding mot protein 35B, RNA binding protein 35B, RNA-binding mot protein 35B, RNA-binding protein 35B.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information