
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis ESAT6 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 886209 |
| Swiss Prot: | |
| Synonyms: | 6 kDa early secretory antigenic target, 6 kDa early secretory antigenic target ESXA, ESAT 6, esaT6, ESXA, ESXA_MYCTU. |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Mycobacterium tuberculosis is a slow-growing obligate aerobic bacillus that causes most cases of tuberculosis (TB). It is a small, rod-like microbe that can withstand weak disinfectants and survive in a dry state for weeks, but can only grow within a host organism. M. tuberculosis has a thick waxy cell wall that is responsible for the typical caseous granuloma formation in tuberculosis. ESAT6 is a protein secreted by M. tuberculosis that induces a strong immune response in infected organisms, making it a strong candidate for the development of a vaccine against tuberculosis. ESAT6 may also be useful in the detection of the disease. Deletion of the ESAT6 gene leads to the loss of virulence of M. tuberculosis. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
| Reacitivity: | Bacteria (Mycobacterium) |