Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human DTYMK/CDC8 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1841 |
Swiss Prot: | |
Synonyms: | CDC8, Deoxythymidylate kinase thymidylate kinase, deoxythymidylate kinase, dTMP kinase, Dtymk, FLJ44192, KTHY_HUMAN, MGC198617, OTTHUMP00000164604, OTTHUMP00000200145, OTTHUMP00000200146, PP3731, Thymidylate kinase, TMPK, TYMK. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |