Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human TUBB4/beta IV Tubulin |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 10381 |
Swiss Prot: | |
Synonyms: | Beta 4, Beta 4 tubulin, beta 5, MC1R, TBB4_HUMAN, TUB B4, TUBB 4, TUBB4, TUBB5, Tubulin 5 beta, Tubulin beta 3, Tubulin beta 4, Tubulin beta 4 chain, Tubulin beta 5, Tubulin beta IV, Tubulin beta-4 chain. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | Beta III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |