Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human BSPRY |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | |
Swiss Prot: | |
Synonyms: | B box and SPRY domain containing, B box and SPRY domain containing protein, B box and SPRY domain-containing protein;B-box and SPRY domain containing, Bspry, BSPRY_HUMAN, FLJ20150, Zetin 1. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |