
| Species: | Rabbit |
| Applications: | WB FC IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human Attractin |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 8455 |
| Swiss Prot: | |
| Synonyms: | ATRN, ATRN_HUMAN, attractin 2, Attractin, attractin-2, DPPT L, DPPT-L, KIAA0548, Mahogany homolog, mahogany protein, MGCA. |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Mahogany (MG), originally identified as a protein involved in pigmentation, acts in conjunction with melanocortin receptors to suppress diet-induced obesity. Mahogany contains a single transmembrane domain, and it is expressed in a broad range of tissues, including the hypothalamus and pigment cells. Mutations within the mahogany gene were shown to rescue agouti-lethal-yellow mutant mice from obesity. The extracellular domain of mouse mahogany is the ortholog of the human protein attractin. Attractin (also designated DPPT-L) is a human serum glycoprotein and is a member of the CUB family of cell adhesion and guidance proteins. Attractin is expressed on activated T cells and is released from the cells 48 to 72 hours after activation. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
| Reacitivity: | Human, Mouse, Rat |