YRP12403-01
[Polyclonal Antibody]
MAML3 Rabbit Polyclonal Antibody
www.yhsbio.com
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC IF |
| Immunogen Range: |
KLH conjugated synthetic peptide derived from human MAML3 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
|
| Swiss Prot: |
|
| Synonyms: |
AV234550, BC049812, CAGH3, ERDA3, GDN, KIAA1816, MAM 2, MAM2, mastermind like 3 Drosophila, MGC59565, mKIAA1816, TNRC3, MAML3_HUMAN. |
| Purification: |
Purified by Protein A. |
| Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: |
The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1. |
| Caculated MW: |
/ |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!