YRP12358-01 [Polyclonal Antibody]
HES7 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human HES7
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   84667
Swiss Prot:  
Synonyms:   bHLH factor Hes7, bHLHb37, Class B basic helix loop helix protein 37, Class B basic helix-loop-helix protein 37, hairy and enhancer of split 7, Hes7, HES7_HUMAN, hHes7, SCDO4, Transcription factor HES 7, Transcription factor HES-7.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   HES7 is a 225 amino acid transcriptional repressor protein. Localized to the nucleus, HES7 represses transcription of N box- and E box-containing promoters. HES7, along with family member HES1, is thought to cooperatively regulate somite formation in the presomitic mesoderm. HES7 may also be essential for coordinated somite segmentation by acting as a segmentation clock. HES7 contains one basic helix-loop-helix (bHLH) domain and one Orange domain. Mutations in HES7 have been found to cause spondylocostal dysostosis, an autosomal recessive disorder characterized by deformities of the chest and spine.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information