ARP8406-01 [Polyclonal Antibody]
SRPX Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   Recombinant protein of human SRPX
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   8406
Swiss Prot:   P78539
Synonyms:   SRPX;DRS;ETX1;SRPX1
Purification:   Affinity purification
Storage:   Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   X-linked retinitis pigmentosa (XLRP) is a retinal degeneration disorder. The most common form of XLRP has been localized to the gene locus RP3 by linkage and deletion analysis. RP3 maps to chromosome Xp21.1 between CYBB and OTC. The sushi-repeat-containing protein, x chromosome (SRPX) gene, also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.
Caculated MW:   52kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information