
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human THEMIS |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 387357 |
| Swiss Prot: | Q8N1K5 |
| Synonyms: | GASP, SPOT, TSEPA, C6orf190, C6orf207, bA325O24.3, bA325O24.4, Protein THEMIS, Thymocyte-expressed molecule involved in selection, THEMIS |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity). |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
| Reacitivity: | Human, Mouse, Rat |

