ARP3000-01
[Polyclonal Antibody]
GUCY2D Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide of human GUCY2D |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
3000 |
| Swiss Prot: |
Q02846 |
| Synonyms: |
LCA, CYGD, LCA1, RCD2, CORD5, CORD6, GUC2D, ROSGC, retGC, GUC1A4, RETGC-1, ROS-GC1 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: |
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. |
| Caculated MW: |
120kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:200-1:2000
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!