ARP3000-01 [Polyclonal Antibody]
GUCY2D Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide of human GUCY2D
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3000
Swiss Prot:   Q02846
Synonyms:   LCA, CYGD, LCA1, RCD2, CORD5, CORD6, GUC2D, ROSGC, retGC, GUC1A4, RETGC-1, ROS-GC1
Purification:   Affinity purification
Storage:   Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Caculated MW:   120kDa
Observed MW:   Refer to Figures
Applications:   WB 1:200-1:2000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information