ARP2875-01
[Polyclonal Antibody]
GPT Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide of human GPT |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
2875 |
| Swiss Prot: |
P24298 |
| Synonyms: |
AAT1, ALT1, GPT1 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: |
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase. |
| Caculated MW: |
55kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:200-1:1000
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!