ARP10076-01 [Polyclonal Antibody]
PTPRU Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   Recombinant protein of human PTPRU
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   10076
Swiss Prot:   Q92729
Synonyms:   FMI, PTP, PCP-2, PTP-J, PTPRO, PTPU2, PTP-PI, PTP-RO, PTPPSI, hPTP-J, R-PTP-U, R-PTP-PSI
Purification:   Affinity purification
Storage:   Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.
Caculated MW:   162kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information