Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human TESK2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 10420 |
Swiss Prot: | |
Synonyms: | Dual specicity testis specic protein kinase 2, Dual specicity testis-specic protein kinase 2, MGC29168, OTTHUMP00000009093, RP23-109A3.2, Tesk2, TESK2_HUMAN, Testicular protein kinase 2, Testis specic kinase 2. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | TESK2 is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate. Functioning as a dual-specificity protein kinase, TESK2 catalyzes the ATP-dependent phosphorylation of substrates and autophosphorylation on tyrosine and serine/threonine residues, thereby mediating intracellular signal transduction pathways. TESK2 requires magnesium as a cofactor and its catalytic activity is thought to play an important role in meiotic events such as spermatogenesis. TESK2 contains one protein kinase domain that is 65% identical to the kinase domain found in TESK1 (testicular protein kinase 1), suggesting a similar role for these proteins in phosphorylation events. Three isoforms of TESK2 are expressed due to alternative splicing. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |