
| Species: | Rabbit |
| Applications: | WB IHC IF IP |
| Immunogen Range: | Synthetic Peptide of human USO1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 8615 |
| Swiss Prot: | O60763 |
| Synonyms: | TAP, VDP, P115 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner. |
| Caculated MW: | 108 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
| Reacitivity: | Human, Mouse, Rat |