Species: | Rabbit |
Applications: | WB IHC IF IP ChIP ChIPseq |
Immunogen Range: | Synthetic Peptide of human H3K27ac |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 8290 |
Swiss Prot: | Q16695 |
Synonyms: | H3t, H3.4, H3/g, H3FT |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
Caculated MW: | 16 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 ChIP 1:20-1:100 |
Reacitivity: | Human, Mouse, Rat, Other (Wide Range) |