Species: | Rabbit |
Applications: | WB IHC |
Immunogen Range: | Recombinant protein of human EZR |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 7430 |
Swiss Prot: | P15311 |
Synonyms: | CVL, CVIL, VIL2, HEL-S-105 |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
Caculated MW: | 81 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 ICC 1:50-1:100 FC 1:20-1:50 |
Reacitivity: | Human, Mouse, Rat |