Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | Recombinant protein of human BLMH |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 642 |
Swiss Prot: | Q13867 |
Synonyms: | BH, BMH |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. |
Caculated MW: | 52 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
Reacitivity: | Human |