ARP5732-01 [Polyclonal Antibody]
PTGER2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF
Immunogen Range:   Synthetic Peptide of human PTGER2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5732
Swiss Prot:   P43116
Synonyms:   EP2
Purification:   Affinity purification
Storage:   Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. Prostaglandin E2 receptor (53kDa), also known as EP2, is a prostaglandin receptor for prostaglandin E2. It is encoded by the human gene PTGER2. Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Caculated MW:   40 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:100-1:200
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information