ARP5447-01
[Polyclonal Antibody]
POR Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
Recombinant protein of human POR |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
5447 |
Swiss Prot: |
P16435 |
Synonyms: |
CPR, CYPOR, P450R |
Purification: |
Affinity purification |
Storage: |
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008] |
Caculated MW: |
77 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!