ARP50855-01 [Polyclonal Antibody]
PARD6A Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   Synthetic Peptide of human PARD6A
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   50855
Swiss Prot:   Q9NPB6
Synonyms:   PAR6, PAR6C, TAX40, PAR-6A, TIP-40, PAR6alpha
Purification:   Affinity purification
Storage:   Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Caculated MW:   37 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:100
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information