ARP50484-01
[Polyclonal Antibody]
RRM2B Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IF |
Immunogen Range: |
Recombinant protein of human RRM2B |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
50484 |
Swiss Prot: |
Q7LG56 |
Synonyms: |
P53R2, MTDPS8A, MTDPS8B |
Purification: |
Affinity purification |
Storage: |
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described. |
Caculated MW: |
41 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:50-1:100
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!