
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | Recombinant protein of human ATOX1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 475 |
| Swiss Prot: | O00244 |
| Synonyms: | ATX1, HAH1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. |
| Caculated MW: | 7 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
| Reacitivity: | Human |