Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | Recombinant protein of human SUMO4 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 387082 |
Swiss Prot: | Q6EEV6 |
Synonyms: | IDDM5, SMT3H4, SUMO-4, dJ281H8.4 |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. |
Caculated MW: | 11 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |