Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | Recombinant protein of human NSL1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 25936 |
Swiss Prot: | Q96IY1 |
Synonyms: | DC8, MIS14, C1orf48 |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X. |
Caculated MW: | 32 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
Reacitivity: | Human |