ARP2330-01
[Polyclonal Antibody]
FMO5 Rabbit Polyclonal Antibody
www.yhsbio.com
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Room 703,Building 6,333# Guiping
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
Recombinant protein of human FMO5 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
2330 |
Swiss Prot: |
P49326 |
Synonyms: |
|
Purification: |
Affinity purification |
Storage: |
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
Caculated MW: |
60 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!