Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | Recombinant protein of human ETFA |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 2108 |
Swiss Prot: | P13804 |
Synonyms: | EMA, GA2, MADD |
Purification: | Affinity purification |
Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. |
Caculated MW: | 35 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
Reacitivity: | Human, Mouse, Rat |