
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | Recombinant protein of human ETFA |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 2108 |
| Swiss Prot: | P13804 |
| Synonyms: | EMA, GA2, MADD |
| Purification: | Affinity purification |
| Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. |
| Caculated MW: | 35 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
| Reacitivity: | Human, Mouse, Rat |