ARP1910-01
[Polyclonal Antibody]
EDNRB Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
Synthetic Peptide of human EDNRB |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
1910 |
Swiss Prot: |
P24530 |
Synonyms: |
ETB, ET-B, ETBR, ETRB, HSCR, WS4A, ABCDS, ET-BR, HSCR2 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: |
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Caculated MW: |
50 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:100
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!