ARP1789-01
[Polyclonal Antibody]
DNMT3B Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC |
| Immunogen Range: | Synthetic Peptide of human DNMT3B |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 1789 |
| Swiss Prot: | Q9UBC3 |
| Synonyms: | ICF, ICF1, M.HsaIIIB |
| Purification: | Affinity purification |
| Storage: | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011] |
| Caculated MW: | 96 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:200-1:1000 IHC 1:20-1:100 |
| Reacitivity: | Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
