ARP137492-01 [Polyclonal Antibody]
VPS37A Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   Recombinant protein of human VPS37A
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   137492
Swiss Prot:   Q8NEZ2
Synonyms:   HCRP1, PQBP2, SPG53
Purification:   Affinity purification
Storage:   Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
Caculated MW:   44 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:100
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information